Role of the Insulin-like Growth Factor (IGF) Axis in Diseases
Journal article published in 2023 by
Claire M. Perks 
This paper is made freely available by the publisher.
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Abstract
The insulin-like growth factor axis is a multifaceted, complex system that comprises two ligands, IGF-I and IGF-II, receptors (IGF-1R, IGF-IIR, insulin receptor isoforms IR-A and B, and hybrid receptors) six high affinity IGF-binding proteins (IGFBPs 1–6), and IGFBP proteases [...]