Published in
American Society for Microbiology, Microbiology Spectrum, 3(10), 2022
DOI: 10.1128/spectrum.00766-22
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Genomic Surveillance of Clinical Pseudomonas aeruginosa Isolates Reveals an Additive Effect of Carbapenemase Production on Carbapenem Resistance
Journal article published in 2022 by
Luke Diorio-Toth 
,
Sidra Irum,
Robert F. Potter,
Meghan A. Wallace,
Muhammad Arslan,
Tehmina Munir,
Saadia Andleeb,
Carey-Ann D. Burnham ,
Gautam Dantas
,
Sidra Irum,
Robert F. Potter,
Meghan A. Wallace,
Muhammad Arslan,
Tehmina Munir,
Saadia Andleeb,
Carey-Ann D. Burnham ,
Gautam Dantas
This paper is made freely available by the publisher.
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Abstract
Pseudomonas aeruginosa is associated with serious infections, and treatment can be challenging. Because of this, carbapenems and β-lactam/β-lactamase inhibitor combinations have become critical tools in treating multidrug-resistant (MDR) P. aeruginosa infections, but increasing resistance threatens their efficacy.