Published in
American Society for Microbiology, Microbiology Spectrum, 3(10), 2022
DOI: 10.1128/spectrum.00580-22
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A tRNA-Acetylating Toxin and Detoxifying Enzyme in Mycobacterium tuberculosis
Journal article published in 2022 by
Francesca G. Tomasi 
,
Alexander M. J. Hall,
Jessica T. P. Schweber,
Charles L. Dulberger,
Kerry McGowen,
Qingyun Liu,
Sarah M. Fortune ,
Sophie Helaine,
Eric J. Rubin
,
Alexander M. J. Hall,
Jessica T. P. Schweber,
Charles L. Dulberger,
Kerry McGowen,
Qingyun Liu,
Sarah M. Fortune ,
Sophie Helaine,
Eric J. Rubin
This paper is made freely available by the publisher.
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Abstract
The global rise in antibiotic-resistant tuberculosis has prompted an urgent search for new drugs. Toxin-antitoxin (TA) systems allow bacteria to adapt rapidly to environmental changes, and Mycobacterium tuberculosis encodes more TA systems than any known pathogen.