Nano-enabled antioxidant and antibacterial biogenic scavenger is the crucial vector for sustainable and next-generation healthcare/pharmaceuticals. The state-of-the-art biogenic nano-scavenger is concerned with developing metal oxide nanostructures, primarily zinc oxide (ZnO) utilizing bio-extracts owing to their unique physicochemical attributes. This unprecedented study explores the antibacterial/antioxidant scavenging efficacies of green synthesized ZnO nanoparticles (NPs) employing Aegle Marmelos (Linn.) rind extract as multifunctional reagent. The morphological and structural outcomes reveal the formation of irregular biogenic ZnO NPs with all essential characteristic traits with modifications due to Aegle Marmelos (Linn.) rind extract. The as-synthesized biogenic nano-scavenger demonstrated excellent antioxidant potency (DPPH inhibitory activity of 85.13%–91.6%). Besides, it exhibited broadband antibacterial activity against six prominent strains of bacteria including K. Pneumoniae, B. subtilis, S. thalpophilum, P. aeruginosa, S. aureus, and E. coli, which is significant in comparison to medical antibiotics. These exceptional outcomes enable the development of biogenic-antibiotics and antioxidants, which are economic, eco-friendly and high-performing and opens window for next-generation pharmaceutical, bioremediation and healthcare strategies.