The research on molybdenum disulphide (MoS2) has progressed remarkably in the last decade, prompted by the increasing interest for this material as a potential candidate in future ultrathin optoelectronic devices. MoS2 is a layered semiconductor with a gap in the visible region, which can be exfoliated down to the mono-layer form. Since the discovery of the exceptional optoelectronic properties of 2D MoS2, Raman spectroscopy has been extensively used as a tool to characterize the structure and thickness of MoS2 films. Recent works on MoS2-metal interfaces have shown that Raman spectra are significantly affected by the interaction with metals. However, a complete understanding of how such interaction modifies the MoS2 vibrational properties is still lacking. Studying this subject with both experimental and theoretical methods will provide fundamental insight into the interface physics of MoS2-metal systems, which is crucial for the fabrication of metal contacts and for the development of metal-assisted synthesis methods. This review summarizes the main results concerning Raman spectroscopy studies of heterosystems between MoS2 and transition metals, providing both a basis and directions for future research.