Dissemin is shutting down on January 1st, 2025

Published in

American Society for Microbiology, Journal of Virology, 18(96), 2022

DOI: 10.1128/jvi.01233-22

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Long-Term Protective Effect of Serial Infections with H5N8 Highly Pathogenic Avian Influenza Virus in Wild Ducks

Journal article published in 2022 by Valentina Caliendo ORCID, Lonneke Leijten, Marco W. G. van de Bildt, Marjolein J. Poen, Adinda Kok ORCID, Theo Bestebroer, Mathilde Richard ORCID, Ron A. M. Fouchier, Thijs Kuiken
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

This study showed that ducks infected with a less-virulent HPAIV developed immunity that was protective against a subsequent infection with a more-virulent HPAIV 9 months later. Following 2014 H5N8 infection, the proportion of birds with detectable influenza nucleoprotein antibody declined from 100% (8/8) in tufted ducks and 78% (7/9) in mallards after 1 month to 33% (2/6) in tufted ducks and 29% (2/7) in mallards after 9 months.