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American Society for Microbiology, mSphere, 2(6), 2021

DOI: 10.1128/msphere.00074-21

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Escherichia coli Nissle 1917 Enhances Innate and Adaptive Immune Responses in a Ciprofloxacin-Treated Defined-Microbiota Piglet Model of Human Rotavirus Infection

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Rotavirus (RV) is a primary cause of malabsorptive diarrhea in children and is associated with significant morbidity and mortality, especially in developing countries. The use of antibiotics exacerbates intestinal microbial imbalance and results in the persistence of RV-induced diarrhea.