Published in
American Society for Microbiology, Microbiology Spectrum, 4(10), 2022
DOI: 10.1128/spectrum.01097-22
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Human Adenovirus Type 26 Infection Mediated by αvβ3 Integrin Is Caveolin-1-Dependent
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Abstract
In order to fulfill its role as a vector, adenovirus needs to successfully deliver its DNA genome to the host nucleus, a process highly influenced by adenovirus intracellular translocation. Thus, cell entry pathway and intracellular trafficking determine functionality of human adenovirus-based vectors.