Published in
American Society for Microbiology, Journal of Clinical Microbiology, 5(59), 2021
DOI: 10.1128/jcm.00089-21
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Reflex Detection of Ciprofloxacin Resistance in Neisseria gonorrhoeae by Use of the SpeeDx ResistancePlus GC Assay
Journal article published in 2021 by
Darren Y. J. Lee 
,
Melinda M. Ashcroft ,
Eric P. F. Chow ,
Michelle Sait,
Vesna De Petra,
Marlene Tschaepe,
Sigrid Lange,
George Taiaroa ,
Catriona S. Bradshaw,
David M. Whiley,
Christopher K. Fairley,
Benjamin P. Howden,
Marcus Y. Chen,
Shivani Pasricha ,
Deborah A. Williamson
,
Melinda M. Ashcroft ,
Eric P. F. Chow ,
Michelle Sait,
Vesna De Petra,
Marlene Tschaepe,
Sigrid Lange,
George Taiaroa ,
Catriona S. Bradshaw,
David M. Whiley,
Christopher K. Fairley,
Benjamin P. Howden,
Marcus Y. Chen,
Shivani Pasricha ,
Deborah A. Williamson
This paper is made freely available by the publisher.
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Abstract
Resistance-guided therapy (RGT) for gonorrhoea may reduce unnecessary use of broad-spectrum antibiotics. When reflexed from the Aptima Combo 2 assay, the ResistancePlus GC assay demonstrated 94.8% sensitivity and 100.0% specificity for Neisseria gonorrhoeae detection.