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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 5(67), 2023

DOI: 10.1128/aac.01505-22

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Antimicrobial Activity of Cefiderocol against the Carbapenemase-Producing Enterobacter cloacae Complex and Characterization of Reduced Susceptibility Associated with Metallo-β-Lactamase VIM-1

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Emergence of cefiderocol resistance among carbapenemase-producing Enterobacterales, particularly those in the Enterobacter cloacae complex (ECC), is becoming of alarming concern; however, the mechanistic basis of this phenomenon remains poorly understood.