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American Physiological Society, American Journal of Physiology - Heart and Circulatory Physiology, 6(322), p. H906-H913, 2022

DOI: 10.1152/ajpheart.00026.2022

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Carotid intima-media thickness and flow-mediated dilation do not predict acute in-hospital outcomes in patients hospitalized with COVID-19

Journal article published in 2022 by Michelle Cristina-Oliveira, Kamila Meireles, Saulo Gil, Fábio Cavalcante Assis ORCID, João Carlos Geber-Júnior ORCID, Samuel Katsuyuki Shinjo, Heraldo Possolo de Souza, Alfredo Nicodemos Cruz Santana ORCID, Paul A. Swinton, Luciano F. Drager ORCID, Bruno Gualano ORCID, Hamilton Roschel ORCID, Tiago Peçanha ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Studies have suggested a role of endothelial dysfunction and atherosclerosis in COVID-19 pathophysiology. In this prospective cohort study, we assessed the prognostic value of carotid intima-media thickness (IMT) and flow-mediated dilation (FMD) in patients with COVID-19. Carotid IMT and FMD were not independent predictors of major outcomes. These results suggest that other risk factors may be the main drivers of clinical outcomes in patients with COVID-19.