PMRT1, a Plasmodium -Specific Parasite Plasma Membrane Transporter, Is Essential for Asexual and Sexual Blood Stage Development
Journal article published in 2022 by
Jan Stephan Wichers 
,
Paolo Mesén-Ramírez ,
Gwendolin Fuchs ,
Jing Yu-Strzelczyk ,
Jan Stäcker ,
Heidrun von Thien,
Arne Alder ,
Isabelle Henshall ,
Benjamin Liffner ,
Georg Nagel ,
Christian Löw ,
Danny W. Wilson,
Tobias Spielmann ,
Shiqiang Gao ,
Tim-Wolf Gilberger
and other authors.
,
Paolo Mesén-Ramírez ,
Gwendolin Fuchs ,
Jing Yu-Strzelczyk ,
Jan Stäcker ,
Heidrun von Thien,
Arne Alder ,
Isabelle Henshall ,
Benjamin Liffner ,
Georg Nagel ,
Christian Löw ,
Danny W. Wilson,
Tobias Spielmann ,
Shiqiang Gao ,
Tim-Wolf Gilberger
and other authors.
This paper is made freely available by the publisher.
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Abstract
Plasmodium falciparum -infected erythrocytes possess multiple compartments with designated membranes. Transporter proteins embedded in these membranes not only facilitate movement of nutrients, metabolites, and other molecules between these compartments, but also are common therapeutic targets and can confer antimalarial drug resistance.