Dissemin is shutting down on January 1st, 2025

Published in

American Association for the Advancement of Science, Science Advances, 25(7), 2021

DOI: 10.1126/sciadv.abd9208

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ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

SPOP mutation disables 53BP1 ubiquitination and exclusion from DNA double-strand break sites and causes genome instability.