The reuse of lignocellulosic biomaterials as a source of clean energy has been explored in recent years due to the large amount of waste that involves human activities, such as those related to agriculture and food. The anaerobic digestion (AD) of plant-based biomass for bioenergy production poses a series of challenges that new technologies are attempting to solve. An improved decomposition of recalcitrant lignocellulose together with an increase in biogas production yield are the main objectives of these new approaches, which also seek the added value of being environmentally friendly. Recent research has reported significant progress in this regard, offering promising outcomes on the degradation of lignocellulose and its subsequent transformation into biomethane by specialized anaerobic microorganisms, overcoming the drawbacks inherent to the process and improving the yield of methane production. The future of the agri–food industry seems to be heading towards the implementation of a circular economy through the introduction of strategies based on the optimized use of lignocellulosic residues as a source of clean and sustainable energy.