Published in
Royal Society of Chemistry, Chemical Science, 30(14), p. 8054-8060, 2023
DOI: 10.1039/d3sc02513f
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Therapeutic efficacy of <sup>211</sup>At-radiolabeled 2,6-diisopropylphenyl azide in mouse models of human lung cancer
Journal article published in 2023 by
Yudai Ode 
,
Ambara R. Pradipta ,
Peni Ahmadi,
Akihiro Ishiwata ,
Akiko Nakamura,
Yasuko Egawa,
Yuriko Kusakari,
Kyohei Muguruma ,
Yang Wang,
Xiaojie Yin,
Nozomi Sato,
Hiromitsu Haba,
Katsunori Tanaka
,
Ambara R. Pradipta ,
Peni Ahmadi,
Akihiro Ishiwata ,
Akiko Nakamura,
Yasuko Egawa,
Yuriko Kusakari,
Kyohei Muguruma ,
Yang Wang,
Xiaojie Yin,
Nozomi Sato,
Hiromitsu Haba,
Katsunori Tanaka
This paper is made freely available by the publisher.
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Abstract
We developed 211At-radiolabeled 2,6-diisopropylphenyl azide (ADIPA) for targeted α-particle therapy. In the experiment using a mouse model, low-dose (70 kBq) administration of ADIPA effectively suppressed tumor growth without causing adverse effects.