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American Society for Microbiology, Microbiology Spectrum, 3(9), 2021

DOI: 10.1128/spectrum.01131-21

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A highly sensitive and specific SARS-CoV-2 spike- and nucleoprotein-based fluorescent multiplex immunoassay (FMIA) to measure IgG, IgA and IgM class antibodies

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological assays with excellent clinical performance are essential for reliable estimation of the persistence of immunity after infection or vaccination. In this paper we present a thoroughly validated SARS-CoV-2 serological assay with excellent clinical performance and good comparability to neutralizing antibody titers.