We present new harmonized ozone time series from two ground-based microwave radiometers in Switzerland: GROMOS and SOMORA. Both instruments have measured hourly ozone profiles in the middle atmosphere (20–75 km) for more than 2 decades. As inconsistencies in long-term trends derived from these two instruments were detected, a harmonization project was initiated in 2019. The goal was to fully harmonize the data processing of GROMOS and SOMORA to better understand and possibly reduce the discrepancies between the two data records. The harmonization has been completed for the data from 2009 until 2022 and has been successful at reducing the differences observed between the two time series. It also explains the remaining differences between the two instruments and flags their respective anomalous measurement periods in order to adapt their consideration for future trend computations. We describe the harmonization and the resulting time series in detail. We also highlight the improvements in the ozone retrievals with respect to the previous data processing. In the stratosphere and lower mesosphere, the seasonal ozone relative differences between the two instruments are now within 10 % and show good correlation (R > 0.7) (except during summertime). We also perform a comparison of these new data series against measurements from the Microwave Limb Sounder (MLS) and Solar Backscatter Ultraviolet Radiometer (SBUV) satellite instruments over Switzerland. Seasonal mean differences with MLS and SBUV are within 10 % in the stratosphere and lower mesosphere up to 60 km and increase rapidly above that point.