Windstorms are a major disturbance factor for European forests. The 2018 Vaia storm, felled large volumes of timber in Italy causing serious ecological and financial losses. Remote sensing is fundamental for primary assessment of damages and post-emergency phase. An explicit estimation of the timber loss caused by Vaia using satellite remote sensing was not yet undertaken. In this investigation, three different estimates of timber loss were compared in two study sites in the Alpine area: pre-existing local growing stock volume maps based on lidar data, a recent national-level forest volume map, and an novel estimation of AGB values based on active and passive remote sensing. The compared datasets resemble the type of information that a forest manager might potentially find or produce. The results show a significant disagreement in the different biomass estimates, related to the methods used to produce them, the study areas characteristics, and the size of the damaged areas. These sources of uncertainty highlight the difficulty of estimating timber loss, unless a unified national or regional European strategy to improve preparedness to forest hazards is defined. Considering the frequent impacts on forest resources that occurred in the last years in the European Union, remote sensing-based surveys targeting forests is urgent, particularly for the many European countries that still lack reliable forest stocks data.