AbstractAn increase in the seasonal cycle amplitude (SCA) of atmospheric CO₂ since the 1960s has been observed in the Northern Hemisphere (NH). However, the underlying dominant drivers are still debated. The peak season CO₂ uptake by vegetation is critical in shaping the CO₂ seasonality. Using satellite‐upscaled gross primary production (GPP) from FLUXCOM and near‐infrared reflectance of vegetation (NIR_V), we demonstrate that peak GPP has increased across the NH over the last two decades. We relate this productivity increase to changes in the CO₂ SCA using an atmospheric transport model. The increased photosynthesis has strongly contributed to CO₂ SCA trends, but with substantial latitudinal and longitudinal variations. Despite a general increase in the CO₂ SCA, there are distinct regional differences. These differences are mainly controlled by regional biosphere carbon fluxes, with the remainder explained by non‐biome factors, including large‐scale atmospheric transport, changes in fossil fuel combustion, biomass burning and oceanic fluxes. Using the global flask and in situ CO₂ measurement sites, we find that SCA trends at high latitude are mainly driven by increasingly productive natural ecosystems, whereas mid latitude sites around the Midwest United States are mainly impacted by intensified agriculture and atmospheric transport. Averaging across the 15 long‐term surface sites, forests contribute 26% (7%) to the SCA trends, while crops contribute 17% (24%) and the combined shrubland, grassland and wetland regions contribute 23% (37%) for simulations driven by FLUXCOM (NIRv) ecosystem fluxes. Our findings demonstrate that satellite inferred trends of ecosystem fluxes can capture the observed CO₂ SCA trend.