The availability of robust and reliable spatial information on ecosystem condition is of increasing importance in informing conservation policy. Recent policy requirements have sparked a renewed interest in conceptual questions related to ecosystem condition and practical aspects like indicator selection, resulting in the emergence of conceptual frameworks, such as the System of Environmental-Economic Accounting - Ecosystem Accounting (SEEA-EA) and its Ecosystem Condition Typology (ECT). However, while such frameworks are essential to ensure that condition assessments are comprehensive and comparable, large-scale practical implementation often poses challenges that need to be tackled within stringent time and cost frames.We present methods and experiences of the national-level mapping and assessment of ecosystem condition in Hungary. The assessments covered the whole country, including all major ecosystem types present. The methodology constitutes four approaches of quantifying and mapping condition, based on different interpretations of naturalness and hemeroby, complemented by two more using properties that ‘overarch’ ecosystem types, such as soil and landscape attributes. In order to highlight their strengths and drawbacks, as well as to help reconcile aspects of conceptual relevance with practical limitations, we retrospectively evaluated the six mapping approaches (and the resulting indicators) against the indicator selection criteria suggested in the SEEA-EA. The results show that the various approaches have different strengths and weaknesses and, thus, their joint application has a higher potential to address the specific challenges related to large-scale ecosystem condition mapping.