Published in
Royal Society of Chemistry, Chemical Science, 18(14), p. 4745-4758, 2023
DOI: 10.1039/d3sc00651d
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Total synthesis of (−)-scabrolide A and (−)-yonarolide
Journal article published in 2023 by
Nicholas J. Hafeman 
,
Steven A. Loskot,
Christopher E. Reimann,
Beau P. Pritchett ,
Scott C. Virgil,
Brian M. Stoltz
,
Steven A. Loskot,
Christopher E. Reimann,
Beau P. Pritchett ,
Scott C. Virgil,
Brian M. Stoltz
This paper is made freely available by the publisher.
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Abstract
A complete account of the total syntheses of scabrolide A and yonarolide is disclosed. Early approaches that failed due to unexpected reactivity are described, which informed the evolution of a successful strategy toward these two natural products.