Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 5(65), 2021
DOI: 10.1128/aac.02621-20
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Impact of Bicarbonate on PBP2a Production, Maturation, and Functionality in Methicillin-Resistant Staphylococcus aureus
Journal article published in 2021 by
Selvi C. Ersoy 
,
Henry F. Chambers,
Richard A. Proctor,
Adriana E. Rosato,
Nagendra N. Mishra,
Yan Q. Xiong,
Arnold S. Bayer
,
Henry F. Chambers,
Richard A. Proctor,
Adriana E. Rosato,
Nagendra N. Mishra,
Yan Q. Xiong,
Arnold S. Bayer
This paper is made freely available by the publisher.
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Abstract
Certain methicillin-resistant Staphylococcus aureus (MRSA) strains exhibit β-lactam susceptibility in vitro , ex vivo , and in vivo in the presence of NaHCO 3 (NaHCO 3 -responsive MRSA). Here, we investigate the impact of NaHCO 3 on factors required for PBP2a functionality.