American Society for Microbiology, Microbiology Spectrum, 2(10), 2022
DOI: 10.1128/spectrum.02446-21
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In order to generate meaningful metabolomic and microbiome data, the method of sample collection is critical. This study utilizes and compares two methods for intestinal tissue collection for evaluation of metabolites and microbiomes, finding that using a brush to sample the microbiome provides valuable data. However, for metabolomics assessment, biopsy samples may still be required.