In central Argentina, the annual rainfall regime shows increasing since the 2nd half of the 20th century. The aim of this work was to evaluate the long-term changes in the intensity of rainfall in the central-north region of Entre Ríos between 1945 and 2019, based only on daily precipitation records aggregated at yearly, monthly and seasonal levels. We used monthly rainfall data for the period 1945–2019 from 6 localities in Province of Entre Rios, Argentina. The change detection analysis has been conceded using Pettitt’s test, von Neumann ratio test, Buishand’s range test and standard normal homogeneity (SNH) test, while non-parametric tests including linear regression, Mann-Kendall and Spearman rho tests have been applied for trend analysis. Like the regional results, this study observed a sustained increase in monthly rainfall to the breaking point in the 1970s, but then the annual rate of increase was even higher. The average annual rainfall in the region prior to that date was 946 mm, while after the same 1150 mm, equivalent to 21.5% higher than the 1945–1977 average and 8.5% higher according to the historical average 1945–2019.