Mounting evidence of chemical disequilibria in the Venusian atmosphere has heightened interest in the search for life within the planet’s cloud decks. Balloon systems are currently considered to be the superior class of aerial platform for extended atmospheric sampling within the clouds, providing the highest ratio of science return to risk. Balloon-based aerial platform designs depend heavily on payload mass and target altitudes. We present options for constant- and variable-altitude balloon systems designed to carry out science operations inside the Venusian cloud decks. The Venus Life Finder (VLF) mission study proposes a series of missions that require extended in situ analysis of Venus cloud material. We provide an overview of a representative mission architecture, as well as gondola designs to accommodate a VLF instrument suite. Current architecture asserts a launch date of 30 July 2026, which would place an orbiter and entry vehicle at Venus as early as November 29 of that same year.