Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification

Kavousi, Maryam; Bos, Maxime M.; Barnes, Hanna J.; Lino Cardenas, Christian L.; Wong, Doris; Lu, Haojie; Hodonsky, Chani J.; Landsmeer, Lennart P. L.; Turner, Adam W.; Kho, Minjung; Hasbani, Natalie R.; de Vries, Paul S.; Bowden, Donald W.; Chopade, Sandesh; Deelen, Joris; Benavente, Ernest Diez; Guo, Xiuqing; Hofer, Edith; Hwang, Shih-Jen; Lutz, Sharon M.; Lyytikäinen, Leo-Pekka; Slenders, Lotte; Smith, Albert V.; Stanislawski, Maggie A.; van Setten, Jessica; Wong, Quenna; Yanek, Lisa R.; Becker, Diane M.; Beekman, Marian; Budoff, Matthew J.; Feitosa, Mary F.; Finan, Chris; Hilliard, Austin T.; Kardia, Sharon L. R.; Kovacic, Jason C.; Kral, Brian G.; Langefeld, Carl D.; Launer, Lenore J.; Malik, Shaista; Hoesein, Firdaus A. A. Mohamed; Mokry, Michal; Schmidt, Reinhold; Smith, Jennifer A.; Taylor, Kent D.; Terry, James G.; van der Grond, Jeroen; van Meurs, Joyce; Vliegenthart, Rozemarijn; Xu, Jianzhao; Young, Kendra A.; Zilhão, Nuno R.; Zweiker, Robert; Assimes, Themistocles L.; Becker, Lewis C.; Bos, Daniel; Carr, J. Jeffrey; Cupples, L. Adrienne; de Kleijn, Dominique P. V.; de Winther, Menno; den Ruijter, Hester M.; Fornage, Myriam; Freedman, Barry I.; Gudnason, Vilmundur; Hingorani, Aroon D.; Hokanson, John E.; Ikram, M. Arfan; Išgum, Ivana; Jacobs, David R.; Kähönen, Mika; Lange, Leslie A.; Lehtimäki, Terho; Pasterkamp, Gerard; Raitakari, Olli T.; Schmidt, Helena; Slagboom, P. Eline; Uitterlinden, André G.; Vernooij, Meike W.; Bis, Joshua C.; Franceschini, Nora; Psaty, Bruce M.; Post, Wendy S.; Rotter, Jerome I.; Björkegren, Johan L. M.; O’Donnell, Christopher J.; Bielak, Lawrence F.; Peyser, Patricia A.; Malhotra, Rajeev; van der Laan, Sander W.; Miller, Clint L.

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Maryam Kavousi
Kavousi et al., 2023

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Nature Research, Nature Genetics, 10(55), p. 1651-1664, 2023

DOI: 10.1038/s41588-023-01518-4

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@article{Kavousi2023,
  author = {Kavousi, Maryam and Bos, Maxime M. and Barnes, Hanna J. and Lino Cardenas, Christian L. and Wong, Doris and Lu, Haojie and Hodonsky, Chani J. and Landsmeer, Lennart P. L. and Turner, Adam W. and Kho, Minjung and Hasbani, Natalie R. and de Vries, Paul S. and Bowden, Donald W. and Chopade, Sandesh and Deelen, Joris and Benavente, Ernest Diez and Guo, Xiuqing and Hofer, Edith and Hwang, Shih-Jen and Lutz, Sharon M. and Lyytikäinen, Leo-Pekka and Slenders, Lotte and Smith, Albert V. and Stanislawski, Maggie A. and van Setten, Jessica and Wong, Quenna and Yanek, Lisa R. and Becker, Diane M. and Beekman, Marian and Budoff, Matthew J. and Feitosa, Mary F. and Finan, Chris and Hilliard, Austin T. and Kardia, Sharon L. R. and Kovacic, Jason C. and Kral, Brian G. and Langefeld, Carl D. and Launer, Lenore J. and Malik, Shaista and Hoesein, Firdaus A. A. Mohamed and Mokry, Michal and Schmidt, Reinhold and Smith, Jennifer A. and Taylor, Kent D. and Terry, James G. and van der Grond, Jeroen and van Meurs, Joyce and Vliegenthart, Rozemarijn and Xu, Jianzhao and Young, Kendra A. and Zilhão, Nuno R. and Zweiker, Robert and Assimes, Themistocles L. and Becker, Lewis C. and Bos, Daniel and Carr, J. Jeffrey and Cupples, L. Adrienne and de Kleijn, Dominique P. V. and de Winther, Menno and den Ruijter, Hester M. and Fornage, Myriam and Freedman, Barry I. and Gudnason, Vilmundur and Hingorani, Aroon D. and Hokanson, John E. and Ikram, M. Arfan and Išgum, Ivana and Jacobs, David R. and Kähönen, Mika and Lange, Leslie A. and Lehtimäki, Terho and Pasterkamp, Gerard and Raitakari, Olli T. and Schmidt, Helena and Slagboom, P. Eline and Uitterlinden, André G. and Vernooij, Meike W. and Bis, Joshua C. and Franceschini, Nora and Psaty, Bruce M. and Post, Wendy S. and Rotter, Jerome I. and Björkegren, Johan L. M. and O’Donnell, Christopher J. and Bielak, Lawrence F. and Peyser, Patricia A. and Malhotra, Rajeev and van der Laan, Sander W. and Miller, Clint L.},
  doi = {10.1038/s41588-023-01518-4},
  journal = {Nature Genetics},
  month = {sep},
  pages = {1651-1664},
  title = {Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification},
  url = {https://oadoi.org/10.1038/s41588-023-01518-4},
  volume = {55},
  year = {2023}
}

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