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American Physiological Society, American Journal of Physiology - Heart and Circulatory Physiology, 3(323), p. H569-H576, 2022

DOI: 10.1152/ajpheart.00291.2022

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Oxygen uptake kinetics and chronotropic responses to exercise are impaired in survivors of severe COVID-19

Journal article published in 2022 by Igor Longobardi ORCID, Danilo Marcelo Leite do Prado, Karla Fabiana Goessler, Matheus Molina Meletti ORCID, Gersiel Nascimento de Oliveira Júnior ORCID, Danieli Castro Oliveira de Andrade, Bruno Gualano ORCID, Hamilton Roschel ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Our findings provide novel data regarding the impact of COVID-19 on submaximal and maximal cardiopulmonary responses to exercise. We showed that V̇o2 kinetics is significantly impaired at both the onset (on-transient) and the recovery phase (off-transient) of exercise in these patients. Furthermore, our results suggest that survivors of severe COVID-19 may have a higher metabolic demand at a walking pace. These findings may partly explain the exertional intolerance frequently observed following COVID-19.