Published in
American Society for Microbiology, Microbiology Spectrum, 2(11), 2023
DOI: 10.1128/spectrum.05074-22
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Extended-Spectrum β-Lactamase Genes Traverse the Escherichia coli Populations of Intensive Care Unit Patients, Staff, and Environment
Journal article published in 2023 by
Robert A. Moran,
Liu Baomo,
Emma L. Doughty,
Yingyi Guo,
Xiaoliang Ba 
,
Willem van Schaik,
Chao Zhuo,
Alan McNally
,
Willem van Schaik,
Chao Zhuo,
Alan McNally
This paper is made freely available by the publisher.
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Abstract
ESBL resistance significantly impacts clinical management of E. coli infections in hospitals globally. It is important to understand the structures of ESBL-EC populations carried by hospital patients and staff, their capacity to persist in hospital environments, and the dynamics of mobile genes that drive the spread of ESBL resistance.