American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 1(66), 2022
DOI: 10.1128/aac.01652-21
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Echinocandins are frontline antifungal agents in the management of invasive infections due to multidrug resistant Candida auris . The study aimed to evaluate echinocandin resistance in C. auris isolates of multicentric origin, identify the resistance mechanism, and analyze the pharmacodynamic response to caspofungin in a neutropenic mouse model of infection.