Published in
American Society for Microbiology, Journal of Clinical Microbiology, 3(61), 2023
DOI: 10.1128/jcm.01859-22
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Metagenomic Next-Generation Sequencing of Plasma for Diagnosis of COVID-19-Associated Pulmonary Aspergillosis
Journal article published in 2023 by
Martin Hoenigl 
,
Matthias Egger ,
Jessica Price,
Robert Krause,
Juergen Prattes,
P. Lewis White
,
Matthias Egger ,
Jessica Price,
Robert Krause,
Juergen Prattes,
P. Lewis White
This paper is made freely available by the publisher.
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Abstract
Timely diagnosis remains an unmet need in non-neutropenic patients at risk for aspergillosis, including those with COVID-19-associated pulmonary aspergillosis (CAPA), which in its early stages is characterized by tissue-invasive growth of the lungs with limited angioinvasion. Currently available mycological tests show limited sensitivity when testing blood specimens.