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American Association for the Advancement of Science, Science Advances, 16(7), 2021

DOI: 10.1126/sciadv.abf1333

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A nonviral, nonintegrating DNA nanovector platform for the safe, rapid, and persistent manufacture of recombinant T cells

Journal article published in 2021 by Matthias Bozza ORCID, Alice De Roia, Margareta P. Correia ORCID, Aileen Berger ORCID, Alexandra Tuch ORCID, Andreas Schmidt, Inka Zörnig, Dirk Jäger, Patrick Schmidt ORCID, Richard P. Harbottle ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Autosomally replicating episomal DNA nanovectors allow clinical-scale CAR-T cell manufacturing.