Fusobacterium nucleatum Secretes Outer Membrane Vesicles and Promotes Intestinal Inflammation
Journal article published in 2021 by
Melinda A. Engevik 
,
Heather A. Danhof ,
Wenly Ruan ,
Amy C. Engevik ,
Alexandra L. Chang-Graham ,
Kristen A. Engevik ,
Zhongcheng Shi ,
Yanling Zhao,
Colleen K. Brand ,
Evan S. Krystofiak ,
Susan Venable ,
Xinli Liu,
Kendal D. Hirschi ,
Joseph M. Hyser,
Jennifer K. Spinler
and other authors.
,
Heather A. Danhof ,
Wenly Ruan ,
Amy C. Engevik ,
Alexandra L. Chang-Graham ,
Kristen A. Engevik ,
Zhongcheng Shi ,
Yanling Zhao,
Colleen K. Brand ,
Evan S. Krystofiak ,
Susan Venable ,
Xinli Liu,
Kendal D. Hirschi ,
Joseph M. Hyser,
Jennifer K. Spinler
and other authors.
This paper is made freely available by the publisher.
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Abstract
Several studies have identified an increased abundance of Fusobacterium in the intestinal tracts of patients with colon cancer, liver cirrhosis, primary sclerosing cholangitis, gastroesophageal reflux disease, HIV infection, and alcoholism. However, the direct mechanism(s) of action of Fusobacterium on pathophysiological within the gastrointestinal tract is unclear.