Published in

Nature Research, Scientific Reports, 1(10), 2020

DOI: 10.1038/s41598-020-71612-8

Links

Tools

Export citation

Search in Google Scholar

Brazilian Maternal and Child Nutrition Consortium: establishment, data harmonization and basic characteristics

Journal article published in 2020 by Edson Theodoro dos Santos-Neto, Thaís Rangel Bousquet Carrilho, Dayana Rodrigues Farias, Juliana dos Santos Vaz, Nathalia Cristina Freitas Costa, Kathleen M. Rasmussen, Michael E. Reichenheim, Antônio Augusto Moura da Silva, Eric O. Ohuma, Claudia Leite de Moraes, Jennifer A. Hutcheon ORCID, Carrilho Trb, Adauto Emmerich Oliveira, Ana Paula Esteves-Pereira, Farias Dr and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Red circle
Postprint: archiving forbidden
Green circle
Published version: archiving allowed
Data provided by SHERPA/RoMEO

Abstract

AbstractPooled data analysis in the field of maternal and child nutrition rarely incorporates data from low- and middle-income countries and existing studies lack a description of the methods used to harmonize the data and to assess heterogeneity. We describe the creation of the Brazilian Maternal and Child Nutrition Consortium dataset, from multiple pooled longitudinal studies, having gestational weight gain (GWG) as an example. Investigators of the eligible studies published from 1990 to 2018 were invited to participate. We conducted consistency analysis, identified outliers, and assessed heterogeneity for GWG. Outliers identification considered the longitudinal nature of the data. Heterogeneity was performed adjusting multilevel models. We identified 68 studies and invited 59 for this initiative. Data from 29 studies were received, 21 were retained for analysis, resulting in a final sample of 17,344 women with 72,616 weight measurements. Fewer than 1% of all weight measurements were flagged as outliers. Women with pre-pregnancy obesity had lower values for GWG throughout pregnancy. GWG, birth length and weight were similar across the studies and remarkably similar to a Brazilian nationwide study. Pooled data analyses can increase the potential of addressing important questions regarding maternal and child health, especially in countries where research investment is limited.