For a long time, Shanghai’s urban tourism has presented a single-core agglomeration pattern with the Bund area as the core, with the phenomenon of overcrowding in the core area during holidays. The opening of Disneyland in 2016 has had an important impact on the development of Shanghai’s urban tourism, including the spatial network of tourism flows. This study selects the travel notes of domestic tourists to Shanghai from Ctrip.com and sorts out a total of 1419 pieces of valid spatial information before and after the opening of Disneyland. With the help of social network analysis, it analyses the influence of Disneyland on the spatial network of domestic tourism flows in Shanghai. The results show that Disneyland has become a new spatial growth pole of Shanghai urban tourism, with an obvious network nuclear Overhauser effect, which is conducive to alleviating congestion in the Bund area, but the correlation effect of Disneyland on other tourism nodes is not obvious. The connection between high-grade tourism nodes is further enhanced, and some low-grade tourism nodes are more marginalized, showing the Matthew effect of nodes and the combined effects of nodes. Accordingly, this paper puts forward three suggestions. First, to strengthen the optimal design of tourism routes and enhance the connection between Disneyland and other tourism nodes; second, to upgrade low-grade tourism nodes, enhance recognition and strengthen integration with core tourism nodes; and, third, to strengthen top-level planning, provide comprehensive support for Disneyland, enhance its industrial linkage effect and spatial network effect, and promote the sustainable development of Shanghai’s urban tourism.