Existing literature on innovation in the context of public health administration is not abundant. Thus, it is expected that there is no model that synthesizes the mechanisms and domains of innovation regarding public health. This chapter seeks to be a theoretical contribution to the identification of the elements that form the dimensions of organizational innovation in health. This goal is pursued in two ways: on the one hand, by identifying and synthesizing the relevant elements in the literature that relate to innovation in health; and on the other hand, by proposing dimensions and sub-dimensions of investigation that allow this void in the literature to be filled. To this end, 117 articles were identified, 64 of which were selected and analyzed in order to present a theoretical model for analyzing organizational innovation in health. The dimensions identified will serve to guide organizational health managers on how to handle innovation in their organizations, particularly the main areas where this innovation occurs, its scope, and its impacts on the various care models.