Creeping perennial weeds are widely distributed on arable fields. The common control practices are intensive inversion tillage and chemical herbicides. However, these methods are under pressure as they negatively affect non-target species and the environment. The objective of the SusCrop-ERA-NET funded European project ‘AC/DC-weeds’ is to implement agroecological management for creeping perennials in arable farming. Focusing on three important perennial species in central and northern Europe (Sonchus arvensis, Cirsium arvense and Elymus repens), the project addresses these species using and combining different methods. In research, the existing information is checked for the contribution to knowledge. New experimental approaches focus research gaps on biology as well as tools and technologies to enable an agro-ecological management. Paying attention to the needs of farming should raise the probability for a practised agro-ecological management of creeping perennials.