Published in
American Association for the Advancement of Science, Science Advances, 40(7), 2021
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G-CSF secreted by mutant IDH1 glioma stem cells abolishes myeloid cell immunosuppression and enhances the efficacy of immunotherapy
Journal article published in 2021 by
Mahmoud S. Alghamri 
,
Brandon L. McClellan ,
Ruthvik P. Avvari ,
Rohit Thalla,
Stephen Carney ,
Margaret S. Hartlage ,
Santiago Haase,
Maria Ventosa,
Ayman Taher ,
Neha Kamran,
Li Zhang ,
Syed Mohd Faisal ,
Felipe J. Núñez ,
María Belén Garcia-Fabiani ,
Wajd N. Al-Holou
and other authors.
,
Brandon L. McClellan ,
Ruthvik P. Avvari ,
Rohit Thalla,
Stephen Carney ,
Margaret S. Hartlage ,
Santiago Haase,
Maria Ventosa,
Ayman Taher ,
Neha Kamran,
Li Zhang ,
Syed Mohd Faisal ,
Felipe J. Núñez ,
María Belén Garcia-Fabiani ,
Wajd N. Al-Holou
and other authors.
This paper is made freely available by the publisher.
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Abstract
Mutant IDH1 gliomas are infiltrated by nonsuppressive immature myeloid cells, resulting in enhanced response to immunotherapy.