Published in

American Society for Microbiology, Journal of Virology, 21(95), 2021

DOI: 10.1128/jvi.00975-21

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Synergistic Block of SARS-CoV-2 Infection by Combined Drug Inhibition of the Host Entry Factors PIKfyve Kinase and TMPRSS2 Protease

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the coronavirus disease 2019 (COVID-2019) global pandemic. There are ongoing efforts to uncover effective antiviral agents that could mitigate the severity of the disease by controlling the ensuing viral replication.