Published in
American Association for the Advancement of Science, Science Immunology, 65(6), 2021
DOI: 10.1126/sciimmunol.abi4425
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Keratinocyte-intrinsic BCL10/MALT1 activity initiates and amplifies psoriasiform skin inflammation
Journal article published in 2021 by
Zsuzsanna Kurgyis 
,
Larsen Vornholz,
Konstanze Pechloff,
Lajos V. Kemény ,
Tim Wartewig ,
Andreas Muschaweckh ,
Abhinav Joshi ,
Katja Kranen,
Lara Hartjes,
Sigrid Möckel,
Katja Steiger ,
Erik Hameister,
Thomas Volz ,
Mark Mellett ,
Lars E. French
and other authors.
,
Larsen Vornholz,
Konstanze Pechloff,
Lajos V. Kemény ,
Tim Wartewig ,
Andreas Muschaweckh ,
Abhinav Joshi ,
Katja Kranen,
Lara Hartjes,
Sigrid Möckel,
Katja Steiger ,
Erik Hameister,
Thomas Volz ,
Mark Mellett ,
Lars E. French
and other authors.
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Abstract
BCL10/MALT1 signaling in keratinocytes is altered in human sporadic psoriasis and is a critical initiator and amplifier of skin inflammation in mouse models.