Published in
American Association for the Advancement of Science, Science Translational Medicine, 670(14), 2022
DOI: 10.1126/scitranslmed.abo4997
Links
Tools
Advancing beyond the twists and turns of T cell exhaustion in cancer
Journal article published in 2022 by
Verena van der Heide 
,
Etienne Humblin ,
Abishek Vaidya ,
Alice Oliffson Kamphorst
,
Etienne Humblin ,
Abishek Vaidya ,
Alice Oliffson Kamphorst
This paper was not found in any repository, but could be made available legally by the author.
Full text: Unavailable
Published version:
archiving forbidden
Data provided by 
Abstract
Chronic antigen stimulation leads to T cell exhaustion. Nutrient restrictions and other suppressive factors in the tumor microenvironment further exacerbate T cell dysfunction. Better understanding of heterogeneity and dynamics of exhausted CD8 T cells will guide novel therapies that modulate T cell differentiation to achieve more effective antitumor responses.