Published in
American Association for the Advancement of Science, Science Translational Medicine, 670(14), 2022
DOI: 10.1126/scitranslmed.abo3605
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Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment
Journal article published in 2022 by
Nicole Kirchhammer 
,
Marcel P. Trefny ,
Priska Auf der Maur ,
Heinz Läubli ,
Alfred Zippelius
,
Marcel P. Trefny ,
Priska Auf der Maur ,
Heinz Läubli ,
Alfred Zippelius
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Abstract
Immune checkpoint blockade (ICB) has revolutionized cancer treatment. However, resistance to ICB occurs frequently due to tumor-intrinsic alterations or extrinsic factors in the tumor microenvironment. This Viewpoint aims to give an update on recent developments in immunotherapy for solid tumors and highlights progress in translational research and clinical practice.