Published in
Oxford University Press, Clinical Infectious Diseases, 8(71), p. e215-e217, 2020
DOI: 10.1093/cid/ciaa145
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Transmission of NS5A-Inhibitor Resistance-Associated Substitutions among Men Who Have Sex with Men Recently Infected with Hepatitis C Virus Genotype 1a
Journal article published in 2020 by
Guido E. van den Berk,
David A. M. C. van de Vijver,
Stephanie Popping,
Jan den Hollander,
Marjo van Kasteren,
Rosanne Verwijs,
Lize Cuypers,
Mark A. Claassen,
G. E. Van Den Berk,
van den Berk Ge,
Joop E. Arends,
Anja De Weggheleire,
Anne Boerekamps,
Arends Jea,
Richard Molenkamp 
and other authors.
and other authors.
This paper is made freely available by the publisher.
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Abstract
Abstract The transmission of direct-acting antiviral resistance-associated substitutions (RAS) could hamper hepatitis C virus (HCV) cure rates and elimination efforts. A phylogenetic analysis of 87 men who have sex with men recently infected with HCV genotype 1a placed one-third (28/87) in a large cluster, in which 96% harbored NS5A M28V RAS.