Published in

Life Metabolism, 2022

DOI: 10.1093/lifemeta/loac023

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Less is more: seipin, phospholipids, and embryogenesis

Journal article published in 2022 by Bin Liang, Jennifer L. Watts
Distributing this paper is prohibited by the publisher
Distributing this paper is prohibited by the publisher

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Abstract

Abstract In a recent paper published in Life Metabolism, Zhu et al. revealed that mutations that reduce phosphatidylcholine (PC) synthesis rescue embryonic lethality but exacerbate lipid droplet (LD) abnormalities in C. elegans seipin mutants, demonstrating distinct roles for Seipin in embryogenesis and LD formation.