Published in
Royal Society of Chemistry, Chemical Science, 28(13), p. 8417-8428, 2022
DOI: 10.1039/d2sc02319a
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Insight into the broadened substrate scope of nitrile hydratase by static and dynamic structure analysis
Journal article published in 2022 by
Dong Ma,
Zhongyi Cheng 
,
Lukasz Peplowski ,
Laichuang Han,
Yuanyuan Xia,
Xiaodong Hou,
Junling Guo,
Dejing Yin,
Yijian Rao ,
Zhemin Zhou
,
Lukasz Peplowski ,
Laichuang Han,
Yuanyuan Xia,
Xiaodong Hou,
Junling Guo,
Dejing Yin,
Yijian Rao ,
Zhemin Zhou
This paper is made freely available by the publisher.
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Abstract
Mutations of two gating residues at the substrate access tunnel entrance direct the substrate scope of NHases.