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MDPI, Biomolecules, 5(12), p. 629, 2022

DOI: 10.3390/biom12050629

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COVID-19 and the Brain: The Neuropathological Italian Experience on 33 Adult Autopsies

Journal article published in 2022 by Viscardo P. Fabbri, Mattia Riefolo, Tiziana Lazzarotto ORCID, Liliana Gabrielli ORCID, Giovanna Cenacchi ORCID, Carmine Gallo, Raffaele Aspide ORCID, Guido Frascaroli, Rocco Liguori, Raffaele Lodi ORCID, Caterina Tonon, Antonietta D’Errico, Maria Pia Foschini
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Neurological symptoms are increasingly recognized in SARS-CoV-2 infected individuals. However, the neuropathogenesis remains unclear and it is not possible to define a specific damage pattern due to brain virus infection. In the present study, 33 cases of brain autopsies performed during the first (February–April 2020) and the second/third (November 2020–April 2021) pandemic waves are described. In all the cases, SARS-CoV-2 RNA was searched. Pathological findings are described and compared with those presently published.