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American Association for the Advancement of Science, Science Advances, 27(7), 2021

DOI: 10.1126/sciadv.abf5733

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Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens

Journal article published in 2021 by Rui Lopes ORCID, Kathleen Sprouffske ORCID, Caibin Sheng ORCID, Esther C. H. Uijttewaal ORCID, Adriana Emma Wesdorp ORCID, Jan Dahinden, Simon Wengert ORCID, Juan Diaz-Miyar, Umut Yildiz ORCID, Melusine Bleu, Verena Apfel, Fanny Mermet-Meillon, Rok Krese, Mathias Eder, André Vidas Olsen ORCID and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Combination of functional epigenomics and single-cell CRISPR screens reveals that ER exerts its oncogenic role via downstream TFs.