Climate change is an emerging issue for modern agriculture and has generated biotic and abiotic stresses for plants such as cold, high temperature, heat, drought, uneven rainfall, and UV radiations. In addition to these, serious stress factors are emerging related to water availability, nutrient cycling, salinity-sodicity, and pest attacks. In recent years, such phenomena have attracted the research community to avoid the fatal influence of climate change on crop production and obtain more food helping in fulfillment of increasing food demand of population surge. The anthropogenic activities in the agroecosystem are among the major causes for global warming and proportion in climate change. Therefore, it is assumed that identifying various plant hormones and their utilization to improve plant metabolic activities would help maintain plant growth, survival, and production under severe climate change circumstances. This chapter focuses on identifying the key aspects of plant hormones to retard the negative impacts of climate change and support sustainable agriculture.