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American Society for Microbiology, Infection and Immunity, 10(89), 2021

DOI: 10.1128/iai.00728-20

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Strategic Variants of CSP Delivered as SynDNA Vaccines Demonstrate Heterogeneity of Immunogenicity and Protection from Plasmodium Infection in a Murine Model

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Malaria infects millions of people every year, and despite recent advances in controlling disease spread, such as vaccination, it remains a global health concern. The circumsporozoite protein (CSP) has long been acknowledged as a key target in antimalarial immunity.