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Published in

American Society for Microbiology, Journal of Virology, 8(96), 2022

DOI: 10.1128/jvi.00331-22

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An Unusual Aspartic Acid Cluster in the Reovirus Attachment Fiber σ1 Mediates Stability at Low pH and Preserves Trimeric Organization

Journal article published in 2022 by Giulia Glorani ORCID, Max Ruwolt ORCID, Nicole Holton, Bernhard Loll ORCID, Ursula Neu ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

Enteric viruses withstand the highly acidic environment of the stomach during transmission, and many of them use low pH as a trigger for conformational changes associated with entry. For many nonenveloped viruses, the structural basis of these effects is not clear.