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American Association for the Advancement of Science, Science Immunology, 71(7), 2022

DOI: 10.1126/sciimmunol.abo1303

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Understanding T-cell responses to COVID-19 is essential for informing public health strategies

Journal article published in 2022 by Santosha Vardhana ORCID, Lance Baldo ORCID, William G. Morice ORCID, E. John Wherry ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Durable T cell responses to SARS-CoV-2 antigens after infection or vaccination improve immune-mediated viral clearance. To date, population-based surveys of COVID-19 adaptive immunity have focused on testing for IgG antibodies that bind spike protein and/or neutralize the virus. Deployment of existing methods for measuring T cell immunity could provide a more complete profile of immune status, informing public health policies and interventions.